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Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity

Deficiency can cause numbness, tingling, and cognitive fog

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These high linear energy transfer (LET) particles are ionizing radiation capable of damaging cellular DNA, disrupting its replication process and ultimately causing cell death [96]

A vertebra slips out of place, pinching the nerve

In addition to oxidative stress and mitochondrial metabolic disorders causing cell death, abnormal copper levels can induce cell death through ROS, ER and inflammatory responses (178)